Darius Slayton DVOA, Advanced Stats, & Fantasy Rankings

The Indianapolis Colts have released veteran wide receiver Darius Slayton, according to ESPN's Adam Schefter. Slayton signed with the Colts after the team placed wideout Alec Pierce (ankle) on injured reserve and was expected to play a larger role in the offense. Slayton has not appeared in a game with the team this season, having suffered a knee injury in practice before last week's game against the Pittsburgh Steelers. Last season, Slayton caught 37 of 63 targets for 538 yards and a touchdown in 14 games with the New York Giants. While it's unclear whether Slayton will sign with another team this season, the Colts will roll with Laquon Treadwell as their primary outside receiver in the coming weeks. This could also mean that Pierce is trending in the right direction and could return at some point this season.

The Indianapolis Colts downgraded wide receiver Darius Slayton (knee) from questionable to out for their Week 5 contest on Sunday at the Pittsburgh Steelers. Slayton is dealing with a new knee injury, but he was able to practice on a limited basis on Friday. His next chance to make his Colts debut will come in Week 6 against the division-rival Tennessee Titans. Alec Pierce (heel) is on Injured Reserve, and veteran Keenan Allen (groin) is questionable to play this weekend, so Indy's receiving corps is thinned out behind Josh Downs. Laquon Treadwell and Deion Burks are the next men up in the Steel City in Week 5, so quarterback Daniel Jones will not be much of an upside play as a QB2 in two-QB superflex leagues against the Steelers. After being cut by the New York Giants, Slayton signed with the Colts on Sept. 21, but he has yet to play in a game with the team. The 29-year-old caught 37 passes for 538 yards and only one touchdown in 14 games in 2025 in his final season with the G-Men. The Colts' lack of WR depth is one of the reasons they have been mentioned as a potential suitor for Arizona Cardinals receiver Marvin Harrison Jr.

Indianapolis Colts wide receiver Darius Slayton (coach's decision) is a healthy scratch for Sunday's Week 4 contest against the Washington Commanders in London. It seemed like Slayton was in line to make his Colts debut after Keenan Allen (groin) was ruled out, but that's not the case. With Slayton, Allen, and Alec Pierce (heel, IR) on the sideline, the Colts will likely give more offensive snaps to Laquon Treadwell and Ashton Dulin. Both receivers will push for more targets in their role behind No. 1 receiver Josh Downs. Allen's absence creates an opportunity for Treadwell or Dulin to step in as the next man up, but we're not quite sure this offense can support multiple fantasy-relevant receivers every week. Downs remains the only Indianapolis wideout that should be started for now.